中國工程院院士 張偲研究員
副標題:
張偲院士
中國科學(xué)院南海海洋研究所 所長(cháng)
(海洋生物活性物質(zhì)及其化學(xué)生態(tài)學(xué)學(xué)科組責任研究員)
研究興趣與領(lǐng)域
主要從事.海洋生物活性物質(zhì)及其化學(xué)生態(tài)學(xué)和海洋微生物多樣性的研究。
代表性成果簡(jiǎn)介
擔任國家重點(diǎn)研發(fā)計劃項目“南海典型海島生態(tài)建設與生態(tài)物聯(lián)網(wǎng)監測技術(shù)研究與示范”首席科學(xué)家,聚焦“南海生態(tài)安全及其可持續發(fā)展”等核心科技問(wèn)題,牽頭負責南海生態(tài)物聯(lián)網(wǎng)建設示范工程。圍繞“熱帶海洋微生物多樣性的時(shí)空分布特征及其功能”關(guān)鍵生態(tài)工程科技問(wèn)題,開(kāi)展微生物多樣性的觀(guān)測、認知和利用研究,發(fā)展熱帶海洋生態(tài)工程理論,發(fā)明微生物促生態(tài)修復等關(guān)鍵技術(shù),促進(jìn)熱帶海洋生態(tài)保護和生物資源利用的工程化,積極推進(jìn)我國海洋戰略性新興產(chǎn)業(yè)發(fā)展與海洋生態(tài)建設。
學(xué)習經(jīng)歷
1981.09-1985.07:中國海洋大學(xué),理學(xué)學(xué)士
1985.09-1988.07:中國科學(xué)院南海海洋研究所,理學(xué)碩士
1995.09-1998.07:中國科學(xué)院南海海洋研究所,理學(xué)博士
工作經(jīng)歷
1998.08-至今:中國科學(xué)院南海海洋研究所,責任研究員
2006.10-2009.06:中國科學(xué)院南海海洋研究所,副所長(cháng)(主持工作)
2009.07-至今:中國科學(xué)院南海海洋研究所,所長(cháng)
2013.12-至今:中國工程院院士
獲獎與榮譽(yù)
1. 國家技術(shù)發(fā)明獎二等獎(第一,2004)
2. 獲國務(wù)院特殊津貼(2004)
3. 國家科技進(jìn)步獎二等獎(第一,2007)
4. “973”項目首席科學(xué)家(2010)
5. 何梁何利基金科技創(chuàng )新獎(2011)
6. 中國工程院院士(2013)
7. 第十五屆中國專(zhuān)利優(yōu)秀獎(第一,2013)
8. 中科院特聘核心骨干研究員(2015)
9. 首屆全國創(chuàng )新?tīng)幭泉劊?/span>2017)
10. 廣東省突出貢獻獎(2020)
學(xué)術(shù)兼職
1. 中國海洋學(xué)會(huì )熱帶海洋分會(huì )主任委員(2012-2022)
2. 中國海洋學(xué)會(huì )常務(wù)理事(2010-2020)
3. 中國海洋與湖沼學(xué)會(huì )常務(wù)理事(2007-2022)
4. 《熱帶海洋學(xué)報》主編(2014-至今)
5. 《中國海洋藥物》編委(2013-至今)
6.
代表性學(xué)術(shù)成果
論文發(fā)表
35. Weimao Zhong, Yuchan Chen, Zhimao Mai, Xiaoyi Wei, Junfeng Wang, Qi Zeng, Xiayu Chen, Xinpeng Tian, Weimin Zhang, Fazuo Wang, * and Si Zhang*. Euroticins A and B, Two Pairs of Highly Constructed Salicylaldehyde Derivative Enantiomers from a Marine-Derived Fungus Eurotium sp.SCSIO F452. The Journal of Organic Chemistry. 2020. 85(19): 12754-12759
34. ZHONG Weimao, WANG Junfeng, SHI Xuefeng, WEI Xiaoyi, CHEN Yuchan, ZENG Qi, XIANG Yao, CHEN Xiayu, TIAN Xinpeng, XIAO Zhihui, ZHANG Weimin, WANG Fazuo*, ZHANG Si*. Eurotiumins A–E, Five New Alkaloids from the Marine-Derived Fungus Eurotium sp. SCSIO F452. Marine Drugs. 2018,16,4,1-10
33. Jie Li*, Weiqi kuang, Lijuan Long, Si Zhang. Production of quorum sensing signals by bacteria in the coral mucus layer. Coral Reefs, 2017, 36: 1235-1241.
32. Yin, H*, Wei, Y, Chen, R, Zhang, S*, Long, L, Yin, H, Tian, X, He, W. Identifying Natural syNergist from Pongamia pinnata Using High-Speed Counter-Current Chromatography Combined with Isobolographic Analysis. Molecules 2017, 22 (3), 397.
31. Jie Li*, Farooq Azam, Si Zhang. Outer membrane vesicles containing signalling molecules and active hydrolytic enzymes released by a coral pathogen Vibrio shilonii AK1. Environmental Microbiology, 2016, 18: 3850-3866.
30. Zhimao Mai, Hongfei Su, Si Zhang*. Characterization of a metagenome-derived beta-glucosidase and its application in conversion of polydatin to resveratrol, Catalysts, 2016.3.01, 6(3).
29. Lizhen Li#, Jian Yang#, Jie Li, Lijuan Long, Yunzhu Xiao, Xinpeng Tian, Fazuo Wang, Si Zhang*. Role of two amino acid residues’ insertion on thermal stability of thermophilic a-amylase AMY121 from a deep sea bacterium Bacillus sp. SCSIO 15121. Bioprocess and Biosystems Engineering. 2015,38(5):871-879
28. Jian Yang#, Jie Li, Yunfeng Hu, Lizhen Li, Lijuan Long, Fazuo Wang, Si Zhang*. Characterization of a thermophilic hemoglobin-degrading protease from Streptomyces rutgersensis SCSIO 11720 and its application in antibacterial peptides production. Bioprocess and Biosystems Engineering. 2015,20(1):79-90
27. Jie Li, Qi Chen, Li-Juan Long, Jun-De Dong, Jian Yang, Si Zhang*. Bacterial dynamics within the mucus, tissue and skeleton of the coral Porites lutea during different seasons. Scientific Reports. 2014,4:7320
26. Li, L.; Yang, J.; Li, J.; Long, L.; Xiao, Y.; Tian, X.; Wang, F.; Zhang, S*. Role of two amino acid residues’ insertion on thermal stability of thermophilic α-amylase AMY121 from a deep sea bacterium Bacillus sp. SCSIO 15121. Bioprocess and Biosystems Engineering. 2014,1-9
25. Jie Li, Jun-De Dong, Jian Yang, Xiong-Ming Luo, Si Zhang*. Detection of polyketide synthase and nonribosomal peptide synthetase biosynthetic genes from antimicrobial coral-associated actinomycetes. Antonie van Leeuwenhoek. 2014,106:623-635
24. Xiongming Luo*, Yongzhong Huang, Si Zhang*, Hao Yin, Chuanrong Li, Qingxin Li. Five new phenethyl cinnamides from the mangrove associates Micromelum falcatum. Biochemical Systematics and Ecology. 2014,(56):191-195
23. Jian Yang, Jie Li, Zhimao Mai, Xinpeng Tian, Si Zhang*. Purification, characterization, and gene cloning of a cold-adapted thermolysin-like protease from Halobacillus sp SCSIO 20089. Journal of Bioscience and Bioengineering. 2013,115(6):628-632
22. YuJuan Liu, LiJuan Long, Xiaofang Huang, Zhiing You, Fazuo Wang, Jie Li, Changjin Kim, Xinpeng Tian, Si Zhang*. Bacillus oceani sp. nov., a new slightly halophilic bacterium, isolated from a deep sea sediment environment. Antonie van Leeuwenhoek. 2013,104(5):829-836
21. Zhiqing You, Jie Li, Sheng Qin Xinpeng Tian, Fazuo Wang, Si Zhang*. Bacillus abyssalis sp. nov., isolated from a sediment of the South China Sea. Antonie van Leeuwenhoek. 2013,103(5):963-969
20. Xinpeng Tian, Lijuan Long, Sumei Li, Jing Zhang, Ying Xu, Jie He, Jie Li,1 Fazuo Wang, Wenjun Li, ChangSheng Zhang, Si Zhang*. Pseudonocardia antitumoralis sp. nov., a deoxynyboquinone-producing actinom ycete isolated from a deep-sea sediment. International journal of systematic and evolutionary microbiology. 2013,63:893-899
19. Ying Xu, Xinpeng Tian(并列第一), YuJuan Liu,1 Jie Li, Changjin Kim,Hao Yin, Wenjun Li*, and Si Zhang*. Sinomicrobium oceani gen. nov., sp. nov., a member of the family Flavoba cteriaceae isolated frommarinesediment. International journal of systematic and evolutionary microbiology. 2013,63:1045-1050
18. Zhiqing You, Jie Li, Sheng Qin, Xin-Peng Tian, Fazuo Wang, Si Zhang*. Georgenia sediminis sp. nov., a moderate thermophilic actinobacterium isolated from sediment of south china sea. International journal of systematic and evolutionary microbiology 2013,63:4243-4247
17. Jie Li, Sheng Qin, Zhiqing You, Lijuan Long, Xinpeng Tian, Fazuo Wang, Si Zhang*. Melghirimyces profundicolus sp. nov., isolated from a deep sea sedimentprofundicolus sp. nov., isolated from a deep sea sediment. International journal of systematic and evolutionary microbiology 2013,63(12):4552-4556
16. Hao Yin*, Si Zhang*, Lijuan Long, Hang Yin, Xinpeng Tian, Xiongming Luo, Haihan Nan, Sha He. The separation of flavonoids from Pongamia pinnata using combination columns in high-speed counter-current chromatography with a three-phase solvent system. Journal of Chromatography A. 2013,1315(0):80-85
15. Li, J., Long, L.-J., Yang, L.-L., Xu, Y., Wang, F.-Z., Li, Q.-X., Zhang, S*, Li, W.-J*. Janibacter alkaliphilus sp. nov., isolated from coral Anthogorgia sp. Antonie Van Leeuwenhoek International Journal of General and Molecular Microbiology. 2012, 102, (1), 157-162
14. Tian, X.-P., Xu, Y., Zhang, J., Li, J., Chen, Z., Kim, C.-J., Li, W.-J., Zhang, C.-S., Zhang, S.* Streptomyces oceani sp nov., a new obligate marine actinomycete isolated from a deep-sea sample of seep authigenic carbonate nodule in South China Sea. Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology. 2012, 102, (2), 335-343.
13. Tian, X.-P., Long, L.-J., Wang, F.-Z., Xu, Y., Li, J., Zhang, J., Zhang, C.-S., Zhang, S.*, Li, W.-J.* Streptomyces nanhaiensis sp nov., a marine streptomycete isolated from a deep-sea sediment. International Journal of Systematic and Evolutionary Microbiology. 2012, 62, 864-868
12. Luo, X., He, W., Yin, H., Li, Q., Liu, Q., Huang, Y., Zhang, S.,* Two New Coumarins from Micromelum falcatum with Cytotoxicity and Brine Shrimp Larvae Toxicity. Molecules. 2012, 17, (6), 6944-6952
11. Xiao, Z.-H., Wang, F.-Z., Sun, A.-J., Li, C.-R., Huang, C.-G., Zhang, S.* A New Triterpenoid Saponin from Abrus precatorius Linn. Molecules. 2012, 17, (1), 295-302
10. Li, J., Yang, J., Zhu, W.-Y., He, J., Tian, X.-P., Xie, Q., Zhang, S.*, Li, W.-J.* Nocardiopsis coralliicola sp. nov., isolated from the gorgonian coral, Menella praelonga. International journal of systematic and evolutionary microbiology. 2012, 62, (Pt 7), 1653-8
9. Li, J., Zhang, G.-T., Yang, J., Tian, X.-P., Wang, F.-Z., Zhang, C. S., Zhang, S.*, Li, W.-J.*. Marininema mesophilum gen. nov., sp nov., a thermoactinomycete isolated from deep sea sediment, and emended description of the family Thermoactinomycetaceae. International journal of systematic and evolutionary microbiology. 2012, 62, 1383-1388
8. Jie Li, Jian Yang, Wen-Yong Zhu, Jie He, Xin-Peng Tian, Qiong Xie, Si Zhang*, Wen-Jun Li. Nocardiopsis coralliicola sp. nov., isolated from the gorgonian coral, Menella praelonga. International journal of systematic and evolutionary microbiology. 2012, 62, 2517-2521.
7. Zhihui Xiao, Fazuo Wang, Hao Yin, Aijun Sun,Chuanrong Li, Qingxin Li,and Si Zhang*. A NEW FLAVANONE FROM Abrus precatorius. Chemistry of Natural Compounds. 2012, 48(4): 565-567
6. Wang, F.; Tian, X.; Huang, C.; Li, Q.; Zhang, S.*,Marinactinones A-C, new gamma-pyrones from marine actinomycete Marinactinospora thermotolerans SCSIO 00606.,J. Antibiot.,2011, 64 (2):189-92.
5. Si Zhang*,Lijuan Long,Effects of glycopeptides on development, growth and non-specific immunity of pearl oyster Pinctada fucata (Gould),2010,Aquaculture Nutrition, 16: 520-527
4. Xin-Peng Tian, Shu-Kun Tang, Jun-Ded Dong, Yu-Qin Zhang, Li-Hua Xu, Si Zhang* and Wen-Jun Li*. Marinactinospora thermotolerans gen. nov., sp. nov., a novel marine actinomycete isolated from a sediment in the northern South China Sea. Int J Syst Evol Microbiol. 2009, 59: 948 - 952.
3. Xin-Peng Tian, Yu-Qin Zhang, Qing-Xin Li, Xiao-Yang Zhi,Shu-Kun Tang, Si Zhang* and Wen-Jun Li*. Streptomyces nanshensis sp. nov., isolated from Nansha Islands of South China Sea. Int J Syst Evol Microbiol. 2009,59:745-749.
2. Xin-Peng Tian, Xiao-Yang Zhi, Yun-Qi Qiu, Yu-Qin Zhang, Shu-Kun Tang, Li-Hua Xu, Si Zhang* and Wen-Jun Li.Sciscionella marina gen. nov., sp. nov., a novel marine actinomycete isolated from a sediment in the northern south China Sea. Int J Syst Evol Microbiol. 2009,59:222-228.
1. Hao Yin, Si. Zhang*, et al. Preparative isolation and purification of two benzoxazinoid glucosides from Acanthus ilicifolius L. by high-speed counter-current chromatography. Journal of Chromatography A. 2008,1205(1-2):177-18.
撰寫(xiě)專(zhuān)著(zhù)
1. 《三亞灣生態(tài)環(huán)境與生物資源》(2007),主編:黃良民、張偲,科學(xué)出版社
2. 《中國海洋微生物多樣性》(2013) ,主編:張偲,出版社: 科學(xué)出版社
授權專(zhuān)利
1. 一種海洋放線(xiàn)菌發(fā)酵提取物及其組合物和在抗生物污損的應用,ZL200810220427.7 張偲,羅雄明,尹 浩,漆淑華,田新朋
2. 一種魷魚(yú)內臟提取的小肽及其制備方法、組合物和作為海洋水產(chǎn)飼料蛋白源的用途,ZL201010272510.6 張偲,羅雄明,尹浩,齊振雄,李慶欣
3. 一種海洋來(lái)源Bacillus barbaricus SCSIO 02429以及用它制備魷魚(yú)小肽的方法,香港專(zhuān)利授權:CN101974460B;日本專(zhuān)利授權號:特願2012-535620 張偲,尹浩,羅雄明,齊振雄,田新朋
4. 一種海洋細菌適冷蛋白酶及其編碼基因和應用,ZL201210180260.2 張偲,楊鍵,李潔,麥志茂,田新朋,尹浩
5. 一種假諾卡氏菌及利用其制備deoxynyboquinone的方法,ZL201110231994.4 張偲,張長(cháng)生,田新朋,李蘇梅,張文軍,張海波,張光濤,尹浩,鞠建華
6. 一種新穎的糖苷水解酶家族44的纖維素酶及其編碼基因和應用,ZL201310124139.2 張偲,麥志茂,楊鍵,李潔,錢(qián)雪橋,尹團,張士忠
7. 一種丙酸桿菌及其在生產(chǎn)葉酸和煙酸中的應用,ZL 2017113052614張偲,李潔,陳志豪,尹團,錢(qián)雪橋
8. 一株產(chǎn)胞外多糖可固沙的溶桿菌SCSIO 17111及其應用,ZL 2018106095003,張偲,王琳,李潔
學(xué)科組建設
責任研究員:張偲
研究員:尹浩、王發(fā)左、李潔、潘劍宇
副研究員:陳華
助理研究員:麥志茂、呂麗娜(特別研究助理)、王琳(特別研究助理)、蔡冰娜、萬(wàn)鵬
博士后:陳煜
行政人員:李慶欣、鄭怡聰
博士研究生:曾奇(2018)、鄒易陽(yáng)(2018)、李琦琦(2019)、丁文平(2019)、琚慧敏(2020)、劉自堯(2020)
碩士研究生:黃諭(2020)
已培養博士研究生19名;碩士研究生7名